Clinical Insights: Antiangiogenesis in Cancer Therapy
Part of the Oncology collection
Edited by Bristi Basu, Swethajit Biswas and Simon Pacey
Angiogenesis is considered one of the hallmarks of cancer. However, barring a few notable examples of significant success such as in clear-cell kidney cancer, angiogenesis inhibition as monotherapy has failed to make the profound impact on clinical practice that was initially anticipated. This book presents a succinct guide to angiogenesis inhibitors in clinical development and the evidence for angiogenesis inhibition across a broad range of tumors. It presents updates from the clinical research field and opinions on how antiangiogenic strategies may be optimized for therapeutic benefit.