Emerging Therapeutics for Melanoma

Description

Published January 2012

ISBN: 978-1-78084-032-1

Understanding of the biology of melanoma has increased substantially during the past two decades, with consequent advances in therapeutic approaches and overall disease management. This book addresses diagnosis, prevention, prognosis, treatment and follow up in melanoma. In twelve chapters from international experts, the book provides a comprehensive overview of the current status of understanding and management of melanoma, including discussion of current limitations and suggestions for modification of strategies that could help current promising concepts to yield success in the clinic.

Chapters

1. Melanoma pathophysiology and drug targets
   Giuseppe Palmieri, Carla Rozzo, Giusy Gentilcore & Paolo Antonio Ascierto
2. Melanoma classification, diagnosis and staging
   Mohammed Kashani-Sabet
3. Melanoma prevention
   Pamela B Cassidy, Douglas Grossman & Sancy A Leachman
4. Surgical treatment of melanoma: from excision to sentinel node biopsy
   Nicola Mozzillo & Corrado Caracò
5. Adjuvant therapy in melanoma
   Diwakar Davar, Ahmad A Tarhini & John M Kirkwood
6. Immunostimulatory monoclonal antibodies for melanoma treatment
   Miguel Fernandez de Sanmamed, Jose L Perez-Gracia, Salvador Martín-Algarra & Ignacio Melero
7. New signal transduction inhibitors
   Keith T Flaherty
8. Melanoma vaccines in development
   Ruggero Ridolfi, Laura Ridolfi, Stefania VL Nicoletti & Massimo Guidoboni
9. Melanoma and biomarkers of immunoresponsiveness: predicting the clinical outcome of immunotherapy
   Davide Bedognetti, Ena Wang, Mario Roberto Sertoli & Francesco M Marincola
10. Uveal melanoma
    Paola Queirolo, Graziano Caltabiano & Francesco Spagnolo
11. Management of melanoma brain metastases in the era of targeted therapies Daniela Gonsalves Shapiro, Michael T Shapiro & Wolfram E Samlowski
12. Which therapy for which patient?
    Antoni Ribas